CipherShed started out as a fork of now-discontinued TrueCrypt project. Just like TrueEncrypt, CipherShed is also open-source software. If you have ever used TrueCrypt before then you will have no trouble starting to use CipherShed as it uses a very similar user interface.
CipherShed is an on-the-fly-encryption software that uses virtual encrypted volumes, containers or drives for encryption. Basically you have to create a virtual volume using CipherShed and this virtual volume will be available in the Windows File Explorer just like any other drive. You can now copy any files to this virtual drive and all these files will be instantly encrypted. When you have done using this virtual drive, you can unmount it using the CipherShed interface.
All of these encrypted volumes are saved as encrypted files themselves that can be copied to a removable drive or anywhere else on your hard drive. Without the proper password, nobody can access the contents of these virtual volumes. These volumes are encrypted using very very strong ciphers and are not prone to any brute force attacks.
Apart from the virtual volumes, it can also encrypt system partition, non-system partition or the entire hard drive so that when you boot your computer you are required to supply the decryption password. There is also an option to create a hidden operating system that will not be visible to anyone and only you can use it whenever needed. However, encrypting the entire system partition is not recommended for the ordinary users. Many of these features are aimed at only very advanced users.
Even though it is designed to be a cross-platform software that is supposed to work on Windows, macOS and Linux, packages for macOS and Linux are not available. Users of these operating systems have to compile the software on their own.
You can download CipherShed from https://www.ciphershed.org/.